New technology cures GERD without surgery

Over 15 million Americans suffer from gastroesophageal reflux disease, or GERD. While many patients manage their condition by watching what they eat and popping over-the-counter medications, a new technology can help relieve the burn for good.  

Allen Ahmed, 36, relied on medication for years to control his GERD.

“It was a lot of pain with the acid reflux, very uncomfortable,” Ahmed said. “I would get a lot of chest pain and I would throw up a lot.”

Patients like Ahmed deal with a variety of symptoms including:

  • Burning in the chest or throat
  • A sour taste in the mouth
  • Difficulty swallowing
  • Dry cough or hoarseness
  • Regurgitation of food

When over-the-counter medications didn’t work for Ahmed, his doctor suggested he try a new alternative therapy called Stretta.

“It's a non-surgical, minimally invasive, endoscopically-based procedure where there is a treatment directed at the lower esophagus and the upper part of the stomach to try to reduce the reflux tendencies through various mechanisms,” said Dr. Aaron Tokayer, a gastroenterologist who treated Ahmed at Montefiore Medical Center in New York.

During the procedure, Tokayer placed a catheter through Ahmed’s mouth and into the valve between the stomach and the esophagus. The technology delivers radio frequency energy to the muscles of the lower esophageal sphincter, remodeling the tissue.

“The Stretta procedure is a technique to reduce reflux tendencies in those people, (and is) associated with improved sense of comfort, sense of well-being, better function, less medications or no medications required in the future after the procedure is done,” said Tokayer.

A recent study published in Gastroenterology Research and Practice examined the long-term efficacy of the Stretta procedure in GERD patients and found that it may be a more desirable treatment than either medication or surgery.

For Ahmed, that was exactly the case.

“I felt a little pain here for a few days and it was gone and I started feeling better,” said Ahmed. “I just had wings last night – they were delicious.”

For more information, visit Stretta-Therapy.com

7 Foods That Cause Acid Reflux

When it comes to acid reflux, there are certain foods that are almost universally problematic.

The best strategy is to avoid them entirely. But unfortunately, they often make up over half of many people's diets.

In the 'Reflux Cookbook', authors Jamie Koufman, MD, Jordan Stern, MD, and French master chef Marc Bauer share foods they consider hazardous, based on medical literature and their experience treating thousands of patients.

Chocolate

Bad news for chocolate lovers: Chocolate seems to cause more reflux than any other food. It's a triple whammy:

  1. Chocolate contains caffeine and other stimulants such as theobromine, which cause reflux.
  2. Chocolate is high in fat, and fat causes reflux.
  3. Chocolate is also high in cocoa, and cocoa causes reflux.

Theoretically, dark chocolate isn't as bad as high-fat milk chocolate, but let's face it—all chocolate is bad for reflux.

Soda

Soda and other carbonated beverages are some of the main causes of acid reflux. The bubbles of carbonation expand inside the stomach, and the increased pressure contributes to reflux. Sodas with caffeine and those that are acidic (almost all) are even worse.

Of the beverages that were tested, Coke, Tab, and Diet Pepsi were the most acidic. All carbonated beverages can be a problem, so the authors recommend abstaining completely to avoid acid reflux.

Fried food

Fried food is the single most recognized cause of reflux. It is also the food most often associated with heartburn, which is chest pain from esophageal reflux.

Deep-fried (or even not-so-deep-fried) foods are on the "bad list" because of their high fat content.

Alcohol

Beer, liquor, and wine are believed to contribute to reflux. Many alcoholic beverages are not very acidic. However, alcohol is believed to relax the valve at the bottom of the esophagus (where it joins the stomach), leading to reflux.

Abstain if you can; otherwise, have only one cocktail or glass of wine a day, and completely avoid acidic mixers like orange juice or soda.

High-fat dairy products

All high-fat foods cause reflux. There is no reason to believe that one high-fat butter or cheese is better than another in this regard. If you have reflux and a serious cheese habit, something has to give.

Use a small amount of these foods as flavoring, but not as main ingredients. Low fat is better than no fat.

High-fat meats

Acid reflux is caused by high-fat cuts of meat—beef, pork, lamb—which stay longer in the stomach and increase the chance of acid reflux.

Try cutting back to a lean cut of meat and eat it only once a week.

Caffeine

One cup of coffee or espresso a day is fine, but people who drink coffee all day long are courting reflux—if they don't have it already.

Try switching to chamomile, which is the best herbal tea, or you can have one cup of green tea a day if it is lightly brewed.

Fruit Tied to Fewer Aortic Aneurysms

A diet high in antioxidant-rich fruit may help protect against the development of an abdominal aortic aneurysm (AAA), a Swedish study suggested.

Through 13 years of follow-up, men and women who said they ate more than two servings of fruit a day had a 25% lower risk of developing AAA (HR 0.75, 95% CI 0.62-0.91) compared with those who ate less than 0.7 servings a day, according to Otto Stackelberg, MD, of the Karolinska Institute in Stockholm, and colleagues.

And those who ate the most fruit had a 43% lower risk of developing a ruptured AAA (HR 0.57, 95% 0.36-0.89), the researchers reported in the Aug. 20 issue of Circulation: Journal of the American Heart Association. There were no such associations with vegetable intake.

"A diet high in fruits may help to prevent many vascular diseases, and this study provides evidence that a lower risk of AAA will be among the benefits," Stackelberg and colleagues wrote.

"Berries, especially blueberries and cranberries, are an amazing source of antioxidants which help reverse the oxidation process that results in cardiovascular disease," commented Lori Mackstaller, MD, of the University of Arizona in Tucson.

"If people ate a balanced diet rich in fruits and vegetables -- especially berries -- it could help decrease inflammation," she wrote in an email.

Established risk factors for AAA include older age, male sex, and smoking, but potential dietary risk factors have not been studied in depth.

"Growing evidence indicates that inflammation and oxidative stress may play an important role in AAA pathophysiology, and the redox balance facilitated by antioxidants has made them subject to speculation of having protective effects against AAA development," the authors wrote. Thus, fruits and vegetables -- which contain high levels of antioxidants -- may be protective.

However, only one previous study has explored the association between fruit and vegetable intake and AAA risk. It showed that increased consumption of fruits and vegetables combined was associated with a lower risk of AAA, but it did not examine fruits and vegetables separately or look at the risk of ruptured AAA specifically.

Stackelberg and colleagues looked at data from two large Swedish cohort studies. The current analysis included 44,317 men and 36,109 women ages 46 to 84 at baseline who were followed from 1998 through 2010. All of the participants reported fruit and vegetable consumption at baseline using a 96-item food frequency questionnaire.

Through follow-up, there were 1,086 AAA cases, including 222 ruptured aneurysms. The majority of the cases (86%) and the ruptures (81.5%) occurred in men.

The risk of AAA decreased as consumption of fruit increased (P=0.003 for trend). The association between fruit consumption and AAA risk did not differ by sex.

In an analysis looking at specific types of fruit, no individual fruit was associated with the risk of developing AAA.

Smoking status was the largest confounder of the observed relationships, and in a stratified analysis eating more than two servings of fruit per day was associated with a reduced risk of ruptured AAA in past smokers (HR 0.42, 95% CI 0.19-0.94) and current smokers (HR 0.39, 95% CI 0.17-0.94), but not in those who never smoked (HR 1.02, 95% CI 0.39-2.70). The discrepancy is possibly related to the higher levels of oxidative stress induced by smoking.

Because it is biologically plausible that eating high levels of antioxidants could reduce the risk of developing AAA, it was unexpected that consumption of fruits but not vegetables was associated with AAA risk because both are rich in antioxidants.

"A possible explanation may be the different types of antioxidants found in fruits and vegetables that could have more or less effect on oxidative stress in the aortic wall," the authors wrote.

They acknowledged some limitations of the study, including possible misclassification of dietary intake on the self-administered questionnaires, the possibility that diet could have changed over time, and the lack of routine screening of the aorta, limiting the ability to detect asymptomatic cases of AAA.

UPDATE: This article, originally published Aug. 19, 2013, at 4:00 p.m., was updated with new material (Aug. 19, 2013, at 8:08 p.m.).

Mediterranean diet may reduce the risk of peripheral artery disease

Past studies have suggested that following a Mediterranean diet may reduce the risk of heart attack and stroke. Now, a new analysis of previous research suggests that the diet, supplemented with extra-virgin olive oil or nuts, may reduce the risk of peripheral artery disease. This is according to a research letter published in the journal JAMA.

Peripheral artery disease (PAD) is a condition in which fatty deposits build up in the arteries, restricting blood supply to the arms, legs, stomach or kidneys.

According to the research team, led by Miguel Ruiz-Canela of the University of Navarra in Spain, their study is the first to find a link between a Mediterranean diet and PAD, although the team notes that this same research linked the diet to a reduced risk of stroke and heart attack.

To reach their findings, the investigators analyzed 7,477 participants. Men were aged between 55 and 80 years, while women were aged between 60 and 80 years.

All participants had no sign of PAD or baseline cardiovascular disease, but they did have type 2 diabetes or a minimum of three other cardiovascular risk factors.

The subjects were randomized to one of three diet groups:

  • A Mediterranean diet supplemented with extra virgin olive oil
  • A Mediterranean diet supplemented with nuts, or
  • A low-fat diet with counseling.

All participants were followed from the baseline of the study in 2003 to December 2010 and received a detailed dietary educational program every 3 months.

Lower PAD risk in Mediterranean diet groups

At the midpoint of the study (4.8 years), 89 of the participants developed PAD.

However, the researchers found that groups who followed the Mediterranean diet supplemented with extra-virgin olive oil or nuts had a significantly lower risk of developing PAD, compared with the group following the low-fat diet.

A novel approach to fighting disability from peripheral artery disease

A new approach to treating peripheral artery disease could lead to happier and healthier lives for millions of Americans.

Peripheral artery disease (PAD) limits the flow of oxygen-rich blood to your legs and other parts of the body. This debilitating affliction can make walking painful and affects an estimated 12 million Americans.

“The best thing for this patient population is to try and get them moving,” said Jack Rejeski, a professor of health and exercise science and the director of the Behavioral Medicine Laboratory at Wake Forest.  “If you don’t, they become further impaired, an effect that can severely compromise quality of life.”

He said previous studies have shown supervised treadmill exercise improves mobility and can reduce leg pain during activity for people with PAD.  However, supervised exercise typically is not covered by medical insurance and requires the availability of and access to such programs.

“Unfortunately what happens with PAD is that many people can’t afford supervised care or do not have access to such care,” Rejeski said. “To make matters worse, there has been no evidence that patients with PAD will engage in or can benefit from home-based exercise.”

Until now.

Rejeski is the senior author of a new study that shows for the first time that home-based exercise training can be implemented with success for people with PAD.

The Group Oriented Arterial Leg Study (GOALS) was performed in collaboration with researchers at Northwestern University’s School of Medicine in Chicago with Dr. Mary McDermott as the principal investigator. It appeared in the July 3, 2013 issue of the Journal of the American Medical Association.

Rejeski said participants in the study, aged 65 and older, were randomly assigned to either an intervention group or a control group. Each group met one time weekly for six months. Participants in the intervention group were taught how to develop a home-based program with a focus on goal-setting, self-monitoring and pain management. They were instructed to engage in 50-minute walking exercises at home up to five times a week. Rejeski said the intervention group also benefited from the support of other participants and their group leader. Participants in the control group attended weekly 60-minute lectures by health professionals on topics like managing hypertension, cancer screening and vaccinations.

Prior to and at the end of six months, both groups performed a six-minute walking test. Rejeski said participants in the intervention group were able to walk 53.5 meters further than the control group.

“From a clinical standpoint, this is a significant result,” Rejeski said.  “It will change the current clinical practice guidelines that apply to people with PAD.”

Rejeski said the key to a successful home-based PAD program is a group-mediated approach which provides the support and skills needed to sustain an independent program of physical activity for patients with PAD.

“The participants can identify with other people with the disease and also talk about what has and hasn’t worked for them,” he said. “What this study shows is that if you can get people to understand the value of being physically active, and they can work with and feel supported by others who understand what they facing, they can and often  become accountable for self-managing the symptoms of their disease. “

Rejeski is currently working with his colleagues at Northwestern University on a follow-up grant using mobile technological to deliver this invention to PAD patients so that it can be accessible to a larger segment of the population.

The study, still in its early stages, uses iPhones equipped with accelerometers to track and provide real-time feedback on physical activity performed at home.  The group-based component of the intervention is delivered via telephone and is coordinated and facilitated by a coach.

“This new study will not only help keep participants accountable, but is also a way to feed information back to them so they can monitor their progress,” Rejeski said. “The idea is to merge technology with state-of-the-art methods for behavioral change.”

New technology cures GERD without surgery

Over 15 million Americans suffer from gastroesophageal reflux disease, or GERD. While many patients manage their condition by watching what they eat and popping over-the-counter medications, a new technology can help relieve the burn for good.  

Allen Ahmed, 36, relied on medication for years to control his GERD.

“It was a lot of pain with the acid reflux, very uncomfortable,” Ahmed said. “I would get a lot of chest pain and I would throw up a lot.”

Patients like Ahmed deal with a variety of symptoms including:

  • Burning in the chest or throat
  • A sour taste in the mouth
  • Difficulty swallowing
  • Dry cough or hoarseness
  • Regurgitation of food

When over-the-counter medications didn’t work for Ahmed, his doctor suggested he try a new alternative therapy called Stretta.

“It's a non-surgical, minimally invasive, endoscopically-based procedure where there is a treatment directed at the lower esophagus and the upper part of the stomach to try to reduce the reflux tendencies through various mechanisms,” said Dr. Aaron Tokayer, a gastroenterologist who treated Ahmed at Montefiore Medical Center in New York.

During the procedure, Tokayer placed a catheter through Ahmed’s mouth and into the valve between the stomach and the esophagus. The technology delivers radio frequency energy to the muscles of the lower esophageal sphincter, remodeling the tissue.

“The Stretta procedure is a technique to reduce reflux tendencies in those people, (and is) associated with improved sense of comfort, sense of well-being, better function, less medications or no medications required in the future after the procedure is done,” said Tokayer.

A recent study published in Gastroenterology Research and Practice examined the long-term efficacy of the Stretta procedure in GERD patients and found that it may be a more desirable treatment than either medication or surgery.

For Ahmed, that was exactly the case.

“I felt a little pain here for a few days and it was gone and I started feeling better,” said Ahmed. “I just had wings last night – they were delicious.”

For more information, visit Stretta-Therapy.com

19 signs your thyroid isn’t working right

The thyroid, a butterfly-shaped gland in the neck, can have a dramatic impact on a huge variety of bodily functions, and if you're a woman over 35 your odds of a thyroid disorder are high—more than 30 percent, by some estimates.

At least 30 million Americans have a thyroid disorder and half—15 million—are silent sufferers who are undiagnosed, according to The American Association of Clinical Endocrinologists. Women are as much as 10 times as likely as men to have a thyroid problem, says integrative medicine specialist Dr. Robin Miller, co-author of The Smart Woman’s Guide to MidLife & Beyond.

Located above the Adam's apple, your thyroid produces thyroid hormone (TH), which regulates, among other things, your body's temperature, metabolism, and heartbeat. Things can start to go wrong when your thyroid is under- or over-active. If it's sluggish, it produces too little TH; amped-up and it produces too much. What causes your thyroid to go haywire? It could be genetics, an autoimmune attack, pregnancy, stress, nutritional deficiencies, or toxins in the environment, but experts aren't entirely sure. Because of thyroid hormones far reach in the body—from brain to bowels—diagnosing a disorder can be challenging. Here's how to tell if your thyroid could be on the blink.

You're exhausted

Feeling tired and having no energy are issues associated with lots of conditions, but they're strongly linked with hypothyroidism, the disorder that's the result of too little thyroid hormone. If you're still tired in the morning or all day after a full night's sleep, that's a clue that your thyroid may be underactive. Too little thyroid hormone coursing through your bloodstream and cells means your muscles aren't getting that get-going signal. “Fatigue is the number one symptom I see,” says Miller. “It’s the kind of fatigue where you’re still tired in the morning after a full night’s sleep—that’s a clue that you’re not simply sleep deprived; your thyroid may be underactive.”

Health.com: 7 Tips for the Best Sleep Ever

You're feeling down

Feeling unusually depressed or sad can also be a symptom of hypothyroidism. Why? It's thought that the production of too little thyroid hormone can have an impact on levels of "feel good" serotonin in the brain. With an underactive thyroid turning other body systems down to "low," it's not surprising that your mood might sink there, too.

You feel jittery and anxious

Anxiety and "feeling wired" are associated with hyperthyroidism, when the thyroid gland is making too much thyroid hormone. Flooded with consistent "all systems go" messages, your metabolism and whole body may spin into overdrive. If you feel like you just can't relax, your thyroid may be "hyper."

Health.com: 19 Natural Remedies for Anxiety

Your appetite or taste buds are altered

An increased appetite can be a sign of hyperthyroidism when too much thyroid hormone may have you feeling hungry all of the time. The only upside is that the "hyper" part of the disorder typically offsets the caloric impact of an increased appetite so the end result isn't weight gain.

An underactive thyroid, on the other hand, can mess with your sense of taste and smell.

Your brain feels fuzzy

Sure, it could be caused by sleep deprivation or aging, but cognitive functioning can take a hit when your thyroid is out of whack. Too much thyroid hormone (hyperthyroidism) can cause difficulty concentrating and too little (hypothyroidism) may cause forgetfulness and general brain fog. “When we treat patients for hypothyroidism, they are often surprised at how fast their brain fog goes away and how much sharper they feel,” Miller says. “Many women think it’s just something that comes along with menopause when it really is a sign of a thyroid problem.”

You've lost your interest in sex

Having little or no desire in the sack could be a side effect of a thyroid disorder. Too little thyroid hormone could be a contributor to a low libido, but the cumulative impact of other hypothyroidism symptoms—weight gain, low energy, and body aches and pains—could also play a part.

Health.com: 12 Secrets to Better Orgasms

You're feeling all fluttery

That fluttery feeling you're having may be heart palpitations. It can feel like your heart is actually fluttering or skipping a beat or two, or beating too hard or too quickly. You may notice these feelings in your chest or at pulse points in your throat or neck. Heart flutters or palpitations can be a sign of too many thyroid hormones flooding your system (hyperthyroidism).

Your skin is dry

Skin that's dry and itchy can be a symptom of hypothyroidism. The change in skin texture and appearance is probably due to slowed metabolism (caused by too little thyroid hormone production), which can reduce sweating. Skin without enough moisture can quickly become dry and flaky. Likewise, nails can become brittle and may develop ridges.

Your bowels are unpredictable

People with hypothyroidism sometimes complain of constipation. The disruption in hormone production has likely caused a slowdown of digestive processes.

“There’s just no motility in your gut,” Miller says. “This is one of the top three most common symptoms of hypothyroidism I see.”

On the reverse side of the spectrum, an overactive thyroid gland can cause diarrhea or more frequent bowel movements, which is why they're symptoms of hyperthyroidism.

Your periods have changed

Longer menstrual periods with a heavier flow and more cramps can be a sign of hypothyroidism, where thyroid hormones are in short supply. Periods may be closer together.

With hyperthyroidism, high levels of TH cause menstrual irregularities in a different way. Periods are shorter, farther apart and may be very light. “I always ask my patients about their cycles and if they’re regular,” says Miller. She finds a strong link between irregular cycles and thyroid problems. And if periods are extra-heavy, she checks for anemia, too.

You have painful extremities or muscles

Sometimes you stub a toe or work out too hard—that kind of pain can be explained away. But if you have mysterious or sudden tingling or numbness—or actual pain—in your arms, legs, feet, or hands, that could be a sign of hypothyroidism. Over time, producing too little thyroid hormone can damage the nerves that send signals from your brain and spinal cord throughout your body. The result is those "unexplained" tingles and twinges.

You have high blood pressure

Elevated blood pressure can be a symptom of a thyroid disorder. Both hyperthyroidism and hypothyroidism have been fingered as culprits. By some estimates, people with hypothyroidism have two to three times the risk of developing hypertension. One theory is that low amounts of thyroid hormone can slow heart beat, which can affect pumping strength and blood vessel wall flexibility. Both may cause a rise in blood pressure.

Health.com: 17 Worst Habits for Your Heart

Your thermostat is on the fritz

Feeling cold or having chills is associated with hypothyroidism. The system slow-down caused by an underactive thyroid means less energy is being burned by cells. Less energy equals less heat.

On the other hand, an overactive thyroid puts energy-producing cells into overdrive. That's why people with hyperthyroidism sometimes feel too warm or sweat profusely.

You're hoarse or your neck feels funny

A change in your voice or a lump in your throat could be a sign of a thyroid disorder. One way to check is to take a good look at your neck to see if you can detect any signs of thyroid swelling. You can do a physical check of your own thyroid at home with these directions from The American Association of Clinical Endocrinologists:

Using a hand mirror, watch your throat as you swallow a drink of water. You're looking for any bulges or protrusions in the thyroid area, which is below your Adam's apple but above your collarbones. You may want to try this several times to get a hang of where your thyroid really is. If you see anything that's lumpy or suspicious, see your doctor.

Your sleep schedule is messed up

Want to sleep all of the time? It could be hypothyroidism. A sluggish thyroid can slow bodily functions down to the point where sleeping (even in the daytime) seems like a brilliant idea.

Can't sleep? It could be hyperthyroidism. An overactive thyroid can cause anxiety and rapid pulse, which can make it hard to fall asleep or even wake you in the middle of the night.

You've gained weight

Going up a few dress sizes can be caused by so many things that it's unlikely your doctor will look at weight gain alone as a potential thyroid disorder symptom. However, weight gain is one of the top reasons women show up in Miller’s office for a thyroid checkup. “They’ll tell me that they aren’t eating any more than usual, but they’re gaining weight,” she says. “They are exercising, but they are getting nowhere. They can’t lose it.” It’s almost always due to an underactive thyroid, she says.

On the other end of the scale, a sudden weight loss can signal hyperthyroidism.

Health.com: Lose 8 Pounds in 2 Weeks

Your hair is thinning or falling out

Dry, brittle hair that breaks or falls out can be a sign of hypothyroidism. Too little thyroid hormone disrupts your hair growth cycle and puts too many follicles into "resting" mode, resulting in hair loss—sometimes all over your body including at the outside of your eyebrows. “Lots of my patients come in and tell me that their hairdresser sent them,” says Miller. “They’ll say, ‘My hair stylist said I’m losing my hair and I needed to go ask my doctor about my thyroid.’ The hair salons are more aware of thyroid problems than some doctors!”

An overactive thyroid can also do a number on your hair. Hair issues due to hyperthyroidism typically show up as thinning hair just on your head.

You have trouble getting pregnant

If you've been trying to have a baby for an extended period of time with no luck, an under- or over-active thyroid could be a contributing factor. Difficulty conceiving has been linked to a higher risk of undiagnosed thyroid problems.

Both hypothyroidism and hyperthyroidism can interfere with ovulation, which impairs fertility. Thyroid disorders are also linked to pregnancy complications.

You have high cholesterol

High levels of low-density lipoprotein (LDL) cholesterol that haven't responded to diet, exercise, or medication have been linked to hypothyroidism. Elevated levels of the "bad" cholesterol can be caused by an underactive thyroid and are cause for concern. Untreated hypothyroidism can lead to heart problems, including an enlarged heart and heart failure.

Get your thyroid tested

If you have one or more of these symptoms and suspect it's your thyroid, see your doctor and ask for a thyroid stimulating hormone (TSH) test, Free T3, and Free T4 tests, says Miller. Based on test results, your symptoms, and your physical exam, you may be prescribed synthetic hormones. Testing and treating a thyroid disorder takes a bit of trial-and-error so expect to visit the doctor a few times before the dosage is right.

Push for thyroid treatment

Expect to have to be your own advocate when it comes to your thyroid. Some doctors may be resistant to a thyroid diagnosis, although the American Associated of Clinical Endocrinologists narrowed the TSH range for acceptable thyroid function from 0.5-5.0 to 0.3-3.04 in 2003. That means more women fall into a range that can be treated. “Find a doctor who treats the person, not just the lab tests,” says Miller. “If you’re feeling better at a certain dosage—that should carry just as much weight as the lab results.”

This article originally appeared on Health.com.

19 signs your thyroid isn’t working right

The thyroid, a butterfly-shaped gland in the neck, can have a dramatic impact on a huge variety of bodily functions, and if you're a woman over 35 your odds of a thyroid disorder are high—more than 30 percent, by some estimates.

At least 30 million Americans have a thyroid disorder and half—15 million—are silent sufferers who are undiagnosed, according to The American Association of Clinical Endocrinologists. Women are as much as 10 times as likely as men to have a thyroid problem, says integrative medicine specialist Dr. Robin Miller, co-author of The Smart Woman’s Guide to MidLife & Beyond.

Located above the Adam's apple, your thyroid produces thyroid hormone (TH), which regulates, among other things, your body's temperature, metabolism, and heartbeat. Things can start to go wrong when your thyroid is under- or over-active. If it's sluggish, it produces too little TH; amped-up and it produces too much. What causes your thyroid to go haywire? It could be genetics, an autoimmune attack, pregnancy, stress, nutritional deficiencies, or toxins in the environment, but experts aren't entirely sure. Because of thyroid hormones far reach in the body—from brain to bowels—diagnosing a disorder can be challenging. Here's how to tell if your thyroid could be on the blink.

You're exhausted

Feeling tired and having no energy are issues associated with lots of conditions, but they're strongly linked with hypothyroidism, the disorder that's the result of too little thyroid hormone. If you're still tired in the morning or all day after a full night's sleep, that's a clue that your thyroid may be underactive. Too little thyroid hormone coursing through your bloodstream and cells means your muscles aren't getting that get-going signal. “Fatigue is the number one symptom I see,” says Miller. “It’s the kind of fatigue where you’re still tired in the morning after a full night’s sleep—that’s a clue that you’re not simply sleep deprived; your thyroid may be underactive.”

Health.com: 7 Tips for the Best Sleep Ever

You're feeling down

Feeling unusually depressed or sad can also be a symptom of hypothyroidism. Why? It's thought that the production of too little thyroid hormone can have an impact on levels of "feel good" serotonin in the brain. With an underactive thyroid turning other body systems down to "low," it's not surprising that your mood might sink there, too.

You feel jittery and anxious

Anxiety and "feeling wired" are associated with hyperthyroidism, when the thyroid gland is making too much thyroid hormone. Flooded with consistent "all systems go" messages, your metabolism and whole body may spin into overdrive. If you feel like you just can't relax, your thyroid may be "hyper."

Health.com: 19 Natural Remedies for Anxiety

Your appetite or taste buds are altered

An increased appetite can be a sign of hyperthyroidism when too much thyroid hormone may have you feeling hungry all of the time. The only upside is that the "hyper" part of the disorder typically offsets the caloric impact of an increased appetite so the end result isn't weight gain.

An underactive thyroid, on the other hand, can mess with your sense of taste and smell.

Your brain feels fuzzy

Sure, it could be caused by sleep deprivation or aging, but cognitive functioning can take a hit when your thyroid is out of whack. Too much thyroid hormone (hyperthyroidism) can cause difficulty concentrating and too little (hypothyroidism) may cause forgetfulness and general brain fog. “When we treat patients for hypothyroidism, they are often surprised at how fast their brain fog goes away and how much sharper they feel,” Miller says. “Many women think it’s just something that comes along with menopause when it really is a sign of a thyroid problem.”

You've lost your interest in sex

Having little or no desire in the sack could be a side effect of a thyroid disorder. Too little thyroid hormone could be a contributor to a low libido, but the cumulative impact of other hypothyroidism symptoms—weight gain, low energy, and body aches and pains—could also play a part.

Health.com: 12 Secrets to Better Orgasms

You're feeling all fluttery

That fluttery feeling you're having may be heart palpitations. It can feel like your heart is actually fluttering or skipping a beat or two, or beating too hard or too quickly. You may notice these feelings in your chest or at pulse points in your throat or neck. Heart flutters or palpitations can be a sign of too many thyroid hormones flooding your system (hyperthyroidism).

Your skin is dry

Skin that's dry and itchy can be a symptom of hypothyroidism. The change in skin texture and appearance is probably due to slowed metabolism (caused by too little thyroid hormone production), which can reduce sweating. Skin without enough moisture can quickly become dry and flaky. Likewise, nails can become brittle and may develop ridges.

Your bowels are unpredictable

People with hypothyroidism sometimes complain of constipation. The disruption in hormone production has likely caused a slowdown of digestive processes.

“There’s just no motility in your gut,” Miller says. “This is one of the top three most common symptoms of hypothyroidism I see.”

On the reverse side of the spectrum, an overactive thyroid gland can cause diarrhea or more frequent bowel movements, which is why they're symptoms of hyperthyroidism.

Your periods have changed

Longer menstrual periods with a heavier flow and more cramps can be a sign of hypothyroidism, where thyroid hormones are in short supply. Periods may be closer together.

With hyperthyroidism, high levels of TH cause menstrual irregularities in a different way. Periods are shorter, farther apart and may be very light. “I always ask my patients about their cycles and if they’re regular,” says Miller. She finds a strong link between irregular cycles and thyroid problems. And if periods are extra-heavy, she checks for anemia, too.

You have painful extremities or muscles

Sometimes you stub a toe or work out too hard—that kind of pain can be explained away. But if you have mysterious or sudden tingling or numbness—or actual pain—in your arms, legs, feet, or hands, that could be a sign of hypothyroidism. Over time, producing too little thyroid hormone can damage the nerves that send signals from your brain and spinal cord throughout your body. The result is those "unexplained" tingles and twinges.

You have high blood pressure

Elevated blood pressure can be a symptom of a thyroid disorder. Both hyperthyroidism and hypothyroidism have been fingered as culprits. By some estimates, people with hypothyroidism have two to three times the risk of developing hypertension. One theory is that low amounts of thyroid hormone can slow heart beat, which can affect pumping strength and blood vessel wall flexibility. Both may cause a rise in blood pressure.

Health.com: 17 Worst Habits for Your Heart

Your thermostat is on the fritz

Feeling cold or having chills is associated with hypothyroidism. The system slow-down caused by an underactive thyroid means less energy is being burned by cells. Less energy equals less heat.

On the other hand, an overactive thyroid puts energy-producing cells into overdrive. That's why people with hyperthyroidism sometimes feel too warm or sweat profusely.

You're hoarse or your neck feels funny

A change in your voice or a lump in your throat could be a sign of a thyroid disorder. One way to check is to take a good look at your neck to see if you can detect any signs of thyroid swelling. You can do a physical check of your own thyroid at home with these directions from The American Association of Clinical Endocrinologists:

Using a hand mirror, watch your throat as you swallow a drink of water. You're looking for any bulges or protrusions in the thyroid area, which is below your Adam's apple but above your collarbones. You may want to try this several times to get a hang of where your thyroid really is. If you see anything that's lumpy or suspicious, see your doctor.

Your sleep schedule is messed up

Want to sleep all of the time? It could be hypothyroidism. A sluggish thyroid can slow bodily functions down to the point where sleeping (even in the daytime) seems like a brilliant idea.

Can't sleep? It could be hyperthyroidism. An overactive thyroid can cause anxiety and rapid pulse, which can make it hard to fall asleep or even wake you in the middle of the night.

You've gained weight

Going up a few dress sizes can be caused by so many things that it's unlikely your doctor will look at weight gain alone as a potential thyroid disorder symptom. However, weight gain is one of the top reasons women show up in Miller’s office for a thyroid checkup. “They’ll tell me that they aren’t eating any more than usual, but they’re gaining weight,” she says. “They are exercising, but they are getting nowhere. They can’t lose it.” It’s almost always due to an underactive thyroid, she says.

On the other end of the scale, a sudden weight loss can signal hyperthyroidism.

Health.com: Lose 8 Pounds in 2 Weeks

Your hair is thinning or falling out

Dry, brittle hair that breaks or falls out can be a sign of hypothyroidism. Too little thyroid hormone disrupts your hair growth cycle and puts too many follicles into "resting" mode, resulting in hair loss—sometimes all over your body including at the outside of your eyebrows. “Lots of my patients come in and tell me that their hairdresser sent them,” says Miller. “They’ll say, ‘My hair stylist said I’m losing my hair and I needed to go ask my doctor about my thyroid.’ The hair salons are more aware of thyroid problems than some doctors!”

An overactive thyroid can also do a number on your hair. Hair issues due to hyperthyroidism typically show up as thinning hair just on your head.

You have trouble getting pregnant

If you've been trying to have a baby for an extended period of time with no luck, an under- or over-active thyroid could be a contributing factor. Difficulty conceiving has been linked to a higher risk of undiagnosed thyroid problems.

Both hypothyroidism and hyperthyroidism can interfere with ovulation, which impairs fertility. Thyroid disorders are also linked to pregnancy complications.

You have high cholesterol

High levels of low-density lipoprotein (LDL) cholesterol that haven't responded to diet, exercise, or medication have been linked to hypothyroidism. Elevated levels of the "bad" cholesterol can be caused by an underactive thyroid and are cause for concern. Untreated hypothyroidism can lead to heart problems, including an enlarged heart and heart failure.

Get your thyroid tested

If you have one or more of these symptoms and suspect it's your thyroid, see your doctor and ask for a thyroid stimulating hormone (TSH) test, Free T3, and Free T4 tests, says Miller. Based on test results, your symptoms, and your physical exam, you may be prescribed synthetic hormones. Testing and treating a thyroid disorder takes a bit of trial-and-error so expect to visit the doctor a few times before the dosage is right.

Push for thyroid treatment

Expect to have to be your own advocate when it comes to your thyroid. Some doctors may be resistant to a thyroid diagnosis, although the American Associated of Clinical Endocrinologists narrowed the TSH range for acceptable thyroid function from 0.5-5.0 to 0.3-3.04 in 2003. That means more women fall into a range that can be treated. “Find a doctor who treats the person, not just the lab tests,” says Miller. “If you’re feeling better at a certain dosage—that should carry just as much weight as the lab results.”

This article originally appeared on Health.com.

Bloom’s death raised deep vein thrombosis awareness

Visit NBCNews.com for breaking news, world news, and news about the economy

NBC News correspondent David Bloom was in the middle of a war zone in Iraq when he  was killed by something that takes hundreds of thousands of lives here at home every year: a complication of deep vein thrombosis.  A blood clot in his leg had broken loose and traveled to his lungs. NBC’s Lester Holt reports.

Chronic Kidney Disease on Rise Among U.S. Seniors, Study Shows

The rate of chronic kidney disease in Americans aged 80 and older is increasing, a new study finds.

Previous research showed that the rate of chronic kidney disease in the general U.S. population increased from 1988 to 1994 and from 1999 to 2004, but no figures have been available for people aged 80 and above, the study authors said.

They added that recent studies have found that older adults with chronic kidney disease have high rates of other health problems and are at increased risk for kidney failure, cardiovascular disease and death.

In this study, the researchers examined data from more than 3,500 people aged 80 and older who took part in the U.S. National Health and Nutrition Examination Surveys between 1988 and 2010.

The results appeared in a research letter published online Sept. 24 in the Journal of the American Medical Association.

Kidney function was assessed by a measurement known as glomerular filtration rate (GFR) -- how fast blood flows through tiny filters in the kidney, called glomeruli, per minute. Chronic kidney disease was defined as a GFR of less than 60.

Low GFR was found in about 41 percent of study participants from 1988 to 1994, compared with nearly 50 percent from 1999 to 2004 and about 51 percent from 2005 to 2010, according to a journal news release.

The prevalence of a more severe reduction in kidney function (a GFR of less than 45) was about 14 percent from 1988 to 1994, compared with nearly 19 percent from 1999 to 2004 and almost 22 percent from 2005 to 2010.

The findings point to rising rates of the condition among people 80 and older and suggest that "efforts to address [chronic kidney disease] among the oldest may be necessary," said Dr. C. Barrett Bowling, formerly of the Veterans Affairs Medical Center, in Atlanta, and colleagues.

SOURCE: Journal of the American Medical Association, news release, Sept. 24, 2013

HealthDay

Health Tip: Do You Need Frequent Cholesterol Screenings?

High cholesterol increases your risk of heart attack and stroke. The U.S. Centers for Disease Control and Prevention says current guidelines recommend that adults 20 or older be screened every five years.

But the agency says you may need more frequent cholesterol screenings if:

  • You are a woman 50 or older, or a man 45 or older.
  • Your total cholesterol is 200 mg/dL or higher.
  • Your HDL (good) cholesterol is below 40 mg/dL.
  • In addition to having high cholesterol, you have other risk factors for heart disease or stroke, such as high blood pressure or being overweight.
HealthDay

Can antioxidants in fruits and vegetables protect you and your heart?

Antioxidants are naturally occurring molecules believed to fight against the action of free radicals — originally thought to help prevent diseases like heart disease and cancer. Although fruits and vegetables are a great source of antioxidants, an oversimplified view of the power of antioxidants has caused a boom in the vitamin and dietary supplement industry, with antioxidant vitamins A, C and E topping the list. In fact, 2012 sales in the U.S. totaled nearly $23 billion.

Antioxidant supplements are big business. But can they help your health?

A Complicated Relationship

Despite their growing popularity in the media and on product packaging, there isn’t sufficient evidence that taking antioxidant supplements will improve your health or reduce your risk of cardiovascular disease. In fact, “very limited amount of data suggests they may actually be harmful,” said Dr. Alice H. Lichtenstein, a professor of Nutrition Science and Policy at Tufts University.

The relationship between vitamin supplements and heart health isn’t entirely understood, and some ingredients could have a negative impact on your health. For example, in one study, people took beta-carotene to try reducing their risk of cardiovascular disease.

“It turns out beta-carotene doesn’t actually decrease the risk, and in smokers it actually increased their risk of lung cancer,” Dr. Lichtenstein said. In addition, dietary supplements can have unintended interactions with other medications.

How to Help Your Heart

Instead of taking supplements, the American Heart Association recommends adopting a healthy eating pattern that includes healthy food choices as a way to get all the nutrients you need. The types of foods you eat, and the amount you eat, can affect multiple risk factors, including your cholesterol, weight and blood pressure. To further reduce your risk, don’t smoke and incorporate regular physical activity into your life.

The American Heart Association recommends a diet that’s rich in fruits, vegetables, fish, limited in saturated and trans fats, added sugars and includes low fat and fat free dairy products and high fiber, whole grains. Watch your sodium intake; the sample diet pattern below can help. One of the best reasons to include fruits and vegetables is not just their antioxidants, but because they also contribute a number of important nutrients that most people don’t get enough of, including folate, magnesium, potassium and dietary fiber, as well as vitamins A, C, and K. And they are naturally low in saturated fat and calories!

Look for our Heart-Check mark when grocery shopping to find foods that meet our criteria. And visit our nutrition center for more information on dining out and heart-healthy recipes.

As part of a healthy dietary pattern and healthy lifestyle that includes regular physical activity, an adult consuming 2,000 calories daily should include:

  • Fruits and vegetables: At least 4.5 servings a day
  • Fish (preferably oily fish): At least two 3.5-ounce servings a week
  • Fiber-rich whole grains: At least three 1-ounce-equivalent servings a day
  • Sodium: Less than 1,500 mg a day
  • Sugar-sweetened beverages: No more than 450 calories (36 ounces) a week

These recommendations are also helpful when planning a healthy diet:

  • Nuts, legumes and seeds: At least 4 servings a week
  • Processed meats: No more than 2 servings a week
  • Saturated fat: Less than 7 percent of total energy intake

If you have questions about your specific nutritional needs talk with a dietitian or your healthcare provider.

Air pollution a leading cause of cancer - U.N. agency

LONDON/GENEVA (Reuters) - The air we breathe is laced with cancer-causing substances and is being officially classified as carcinogenic to humans, the World Health Organization's cancer agency said on Thursday.

The International Agency for Research on Cancer (IARC) cited data indicating that in 2010, 223,000 deaths from lung cancer worldwide resulted from air pollution, and said there was also convincing evidence it increases the risk of bladder cancer.

Depending on the level of exposure in different parts of the world, the risk was found to be similar to that of breathing in second-hand tobacco smoke, Kurt Straif, head of the agency's section that ranks carcinogens, told reporters in Geneva.

"Our task was to evaluate the air everyone breathes rather than focus on specific air pollutants," deputy head Dana Loomis said in a statement. "The results from the reviewed studies point in the same direction: the risk of developing lung cancer is significantly increased in people exposed to air pollution."

Air pollution, mostly caused by transport, power generation, industrial or agricultural emissions and residential heating and cooking, is already known to raise risks for a wide range of illnesses including respiratory and heart diseases.

Research suggests that exposure levels have risen significantly in some parts of the world, particularly countries with large populations going through rapid industrialization, such as China.

IARC reviewed thousands of studies on air pollution tracking populations over decades and other research such as those in which mice exposed to polluted air experienced increased numbers of lung tumors.

In a statement released after reviewing the literature, the Lyon-based agency said both air pollution and "particulate matter" - a major component of it - would now be classified among its Group 1 human carcinogens.

That ranks them alongside more than 100 other known cancer-causing substances in IARC's Group 1, including asbestos, plutonium, silica dust, ultraviolet radiation and tobacco smoke.

CARCINOGEN ENCYCLOPAEDIA

Air pollution is highly variable over space and time.

Loomis said there was relatively high exposure in Asia, South Asia, eastern North America, some places in Central America and Mexico, as well as North Africa.

But although both the composition and levels of air pollution can vary dramatically from one location to the next, IARC said its conclusions applied to all regions of the world.

"Our conclusion is that this is a leading environmental cause of cancer deaths," Dr. Christopher Wild, director of IARC, told the news briefing in Geneva.

IARC's ranking monographs program, sometimes known as the "encyclopedia of carcinogens", aims to be an authoritative source of scientific evidence on cancer-causing substances.

It has already classified many chemicals and mixtures that can be components of air pollution, including diesel engine exhaust, solvents, metals and dusts. But this is the first time that experts have classified air pollution as a cause of cancer.

Wild said he hoped the comprehensive evidence would help the WHO, which is revising its global 2005 guidelines on air quality. The U.N. agency makes on recommendations on public health issues to its 193 member states.

Asked why it had taken so long to reach the conclusion, he said that one problem was the time lag between exposure to polluted air and the onset of cancer.

"Often we're looking at two, three or four decades once an exposure is introduced before there is sufficient impact on the burden of cancer in the population to be able to study this type of question," he said.

(Editing by Alison Williams)

Reuters Health

Acid reflux 101: Common causes, symptoms and treatments

Maybe it’s the middle of the night, you wake up coughing, choking.  Or perhaps you are at work, you have a big, greasy meal for lunch, and all of a sudden you feel a burning, stabbing, incessant pain in your chest.  

If these scenarios do sound familiar, you could be one of the 15 million Americans who suffer from heartburn and acid reflux daily.  

Many people have felt the sensation of heartburn, but what exactly is acid reflux?

Acid reflux is the backward flow of stomach acid into the esophagus – the tube that connects the throat to the stomach.  This backward flow becomes possible when the sphincter muscle at the lower end of your esophagus is weak or relaxes at the wrong time.  If the valve or sphincter is open, this allows stomach acid to back up into your esophagus. This reflux can, in turn, cause heartburn – the burning sensation in your chest - along with other symptoms.

When acid reflux and heart burn occurs at least twice a week, and the backwash of acid irritates the lining of your esophagus, doctors will classify this as gastroesophageal reflux disease, or GERD.  

Here are some common symptoms of acid reflux:

  • Chest pain:  Occurs because stomach acid is splashing into the esophagus, and people often mistake it for a heart attack
  • Regurgitation:  A sour or bitter-tasting acid backing up into your throat or mouth
    Pain after meals: If the stomach is overloaded with a big, fatty meal, this can trigger acid production and reflux. 
  • Choking:  Sometimes acid from the stomach makes its way up to the throat and can cause choking.  If you wake up choking, this may be a sign of acid reflux
  • Hoarseness:  Often mistaken for an early cold symptom – this can actually be the result of stomach acid seeping into esophagus and irritating the vocal cords
  • Sore throat: Usually mistaken for seasonal allergies or cold symptom, a sore throat develops from the continuous irritation of acid on throat. An easy way to know to know it’s not a cold, is if you don’t develop other flu or cold- like symptoms
  • Cough:  If you are experiencing a chronic cough and wheezing, this may not be a respiratory issue but rather stomach acid from reflux getting into your lungs
  • Trouble swallowing:  Over time, the continuous cycle of damage and healing after acid reflux can cause scarring.  This, in turn, causes swelling in the esophageal tissue, and a narrowing of the esophagus, resulting in difficulty swallowing

Identifying acid reflux can be tricky, as many of the symptoms are not obvious, and can be easily mistaken for something else, like a heart attack or common cold. However, if left untreated, acid reflux can cause esophagitis, a painful irritation of the esophagus that can lead to bleeding, ulcers and scarring in the esophagus.  Chronic acid reflux has also been linked to Barrett's esophagus, which is an abnormal change in the cells that line the esophagus; a precursor to cancer.

Ok, you have acid reflux.  Now what?

If you have acid reflux, simple lifestyle changes, like losing excess weight, eating smaller meals, and avoiding foods that seem to trigger heartburn can help.

Try to avoid things like:

  • Spicy foods
  • Tomatoes and tomato sauce
  • Garlic
  • Citrus fruit & juices
  • Onion
  • Peppermint
  • Chocolate
  • Fried foods
  • Fatty/greasy foods
  • Salt
  • Coffee (including decaf)
  • Alcohol
  • Soda

Not everyone’s reflux is triggered by the same foods or drinks.  If the items listed above don’t seem to get your acid churning, keep a food journal and note the meals that brought on reflux symptoms.  

If you frequently suffer from acid reflux at night, you may find relief is as simple as avoiding big meals before bed and raising the head of your bed.  Additionally, if you are a smoker, you may want to consider quitting. Smoking can weaken the valve in your throat, leading to acid reflux and heartburn.

Some other natural remedies to ease your heartburn and reflux are chewing gum or taking slippery elm extract.  Chewing gum helps force fluids back into the stomach and flood esophagus with alkaline saliva, neutralizing acids that cause the characteristic burning sensations of heartburn. Slippery elm has been used historically to soothe inflammation, reduce swelling, and heal damaged tissues.  The tree extract is said to thicken the layer of mucous lining the stomach, creating a stronger barrier against acid helping sooth acid reflux.

If these tips do not help, there is a wide array of over-the-counter medication to help ease symptoms. Stronger medications should be taken with care, as they can cause side effects.  And remember, always contact your doctor if you are experiencing chronic and severe symptoms of acid reflux.

Dr. David B. Samadi joined Fox News Channel (FNC) in 2009 as a medical contributor. In this capacity, he contributes to both FNC and Fox News Health.

Colonoscopy Screening Every Ten Years Could Prevent 40% of Colorectal Cancers

According to a large, long-term study from Harvard School of Public Health (HSPH), 40% of all colorectal cancers might be prevented if people underwent regular colonoscopy screening. The new research also supports existing guidelines that recommend that people with an average risk of colorectal cancer should have a colonoscopy every 10 years.

The new study helps address previous uncertainty about the effectiveness of colonoscopy in reducing colorectal cancer incidence and mortality -- particularly among people with cancer that originates in the proximal, or upper part of the colon.

The study appears in the September 19, 2013 edition of the New England Journal of Medicine.

"Colonoscopy is the most commonly used screening test in the U.S. but there was insufficient evidence on how much it reduces the risk of proximal colon cancer and how often people should undergo the procedure," said Shuji Ogino, co-senior author and associate professor in the Department of Epidemiology at HSPH. "Our study provides strong evidence that colonoscopy is an effective technique for preventing cancers of both distal and proximal regions of the colorectum, while sigmoidoscopy alone is insufficient for preventing proximal cancer."

According to the most recent statistics from the Centers for Disease Control and Prevention, nearly 137,000 people in the U.S. were diagnosed with colorectal cancer in 2009, and nearly 52,000 died that year from the disease. Colorectal cancer is the second-leading cause of cancer-related death in the nation.

The researchers analyzed data from 88,902 participants in two long-term studies: the Nurses' Health Study and the Health Professionals Follow-up Study. Based on data from questionnaires that participants filled out every two years between 1988 and 2008, the researchers obtained information on colonoscopy and sigmoidoscopy procedures. They documented 1,815 cases of colorectal cancer and 474 deaths from the disease.

They found that both colonoscopy and sigmoidoscopy -- which screens for tumors in the distal, or lower part of the colorectum -- were associated with decreased risk of either getting colorectal cancer or dying from it. Only colonoscopy decreased the risk for cancers originating in the proximal colon, but not to the degree of its protective effect against distal colorectal cancers. The researchers suggested that colonoscopy's smaller effect in reducing risk for tumors in the proximal colon might be due in part to molecular or biological differences in those cancers.

Other findings include:

  • The researchers estimated that if all participants in the study had undergone colonoscopies, 40% of colorectal cancers -- including 61% of distal cancers and 22% of proximal cancers -- would have been prevented.
  • Sigmoidoscopy alone is likely insufficient for reducing the incidence or death risk of colorectal cancer that originates in the upper colon.
  • People who get a clean bill of health after a colonoscopy have a significantly reduced risk of colorectal cancer for up to 15 years after the procedure, although the data support repeat screening at shorter intervals among individuals with a personal history of adenoma -- a benign tumor of glandular origin that can become malignant over time -- or a family history of colorectal cancer.
  • Colorectal cancers diagnosed within five years of a colonoscopy had different molecular characteristics compared with cancers diagnosed more than five years after a colonoscopy, and they may be difficult to detect or completely remove.

"Each year, more than 1.2 million people are diagnosed with colorectal cancer worldwide. Our findings could help improve and strengthen the current guidelines for colorectal cancer screening," said Reiko Nishihara, lead author and research fellow in the Department of Nutrition at HSPH.